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COVID-19 pathophysiology: A review

by Liqiang Zhou 1  and  Shuxing Xing 1,*
Department of Orthopedics, Chengdu Fifth People's Hospital, Chengdu, 611130, China
Author to whom correspondence should be addressed.
Received: 24 January 2024 / Accepted: 23 February 2024 / Published Online: 25 February 2024


In December 2019, a novel coronavirus, now named as SARS-CoV-2, caused a series of acute atypical respiratory diseases in Wuhan, Hubei Province, China. The disease caused by this virus was termed COVID-19. The virus is transmittable between humans and has caused pandemic worldwide. The number of death tolls continues to rise and a large number of countries have been forced to do social distancing and lockdown. Lack of targeted therapy continues to be a problem. Epidemiological studies showed that elder patients were more susceptible to severe diseases, while children tend to have milder symptoms. Here we reviewed the current knowledge about this disease and considered the potential explanation of the different symptomatology between children and adults.

Copyright: © 2024 by Zhou and Xing. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (Creative Commons Attribution 4.0 International License). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ACS Style
Zhou, L.; Xing, S. COVID-19 pathophysiology: A review. International Journal of Clinical Medical Research, 2024, 2, 21.
AMA Style
Zhou L, Xing S. COVID-19 pathophysiology: A review. International Journal of Clinical Medical Research; 2024, 2(2):21.
Chicago/Turabian Style
Zhou, Liqiang; Xing, Shuxing 2024. "COVID-19 pathophysiology: A review" International Journal of Clinical Medical Research 2, no.2:21.

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