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Treatment of non-small cell lung cancer with the nursing application of chemotherapy and traditional Chinese medicine: A meta-analysis

by Basma M.E. Mohamed 1
1
Clinical Pharmacy department, Faculty of Pharmacy, Beni-suef University, Beni-suef, Egypt
*
Author to whom correspondence should be addressed.
IJCMR  2025 3(4):63; https://doi.org/10.61466/ijcmr3040003
Received: 1 March 2025 / Accepted: 5 July 2025 / Published Online: 1 August 2025
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Abstract

Background

The purpose of the study was to appraise and compare the treatment of non-small cell lung cancer with the nursing application of chemotherapy and traditional Chinese medicine.

Method

Based on the inspection of the meta-analysis data, the odds ratio (OR) and mean difference (MD) with 95% confidence intervals (CIs) were derived by dichotomous random or fixed effect models. 26 papers with a total of 2290 subjects who were available between 2005 and 2021 were included in this meta-analysis.

Results

Traditional Chinese medicine had significantly higher quality of life (OR, 2.79; 95% CI, 1.87-4.16, p<0.001) and clinical efficacy (OR, 2.79; 95% CI, 2.24-3.47, p<0.001), and Karnofsky Performance Status score (OR, 3.03; 95% CI, 1.45-6.34, p=0.003), and lower leukopenia (OR, 0.21; 95% CI, 0.12-0.36, p<0.001), thrombocytopenia (OR, 0.19; 95% CI, 0.13-0.29, p<0.001), myelosuppression (OR, 0.24; 95% CI, 0.10-0.58, p=0.001), hemoglobin decrease (OR, 0.34; 95% CI, 0.12-0.93, p=0.04), nausea and vomiting (OR, 0.16; 95% CI, 0.11-0.22, p<0.001), diarrhea (OR, 0.22; 95% CI, 0.13-0.36, p<0.001), liver damage (OR, 0.17; 95% CI, 0.10-0.28, p<0.001), and kidney damage (OR, 0.30; 95% CI, 0.10-0.90, p=0.03) compared to control in subjects with non-small cell lung cancer.

Conclusions

The data that was looked at showed that using traditional Chinese medicine had significantly higher quality of life and clinical efficacy, and Karnofsky Performance Status score, and lower adverse effects, and hematological toxicity compared to control in subjects with non-small cell lung cancer. However, given that most of the studies comprised a small number as sample size, attention ought to be given to their values.

Keywords: adverse effects; quality of life; Clinical efficacy; hematological toxicity; traditional Chinese medicine; non-small cell lung cancer;
Copyright: © 2025 by Mohamed. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (Creative Commons Attribution 4.0 International License). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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APA Style
Mohamed, B. M. (2025). Treatment of non-small cell lung cancer with the nursing application of chemotherapy and traditional Chinese medicine: A meta-analysis. International Journal of Clinical Medical Research, 3(4), 63. doi:10.61466/ijcmr3040003
ACS Style
Mohamed, B. M. Treatment of non-small cell lung cancer with the nursing application of chemotherapy and traditional Chinese medicine: A meta-analysis. International Journal of Clinical Medical Research, 2025, 3, 63. doi:10.61466/ijcmr3040003
AMA Style
Mohamed B. M.. Treatment of non-small cell lung cancer with the nursing application of chemotherapy and traditional Chinese medicine: A meta-analysis. International Journal of Clinical Medical Research; 2025, 3(4):63. doi:10.61466/ijcmr3040003
Chicago/Turabian Style
Mohamed, Basma M. 2025. "Treatment of non-small cell lung cancer with the nursing application of chemotherapy and traditional Chinese medicine: A meta-analysis" International Journal of Clinical Medical Research 3, no.4:63. doi:10.61466/ijcmr3040003

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ACS Style
Mohamed, B. M. Treatment of non-small cell lung cancer with the nursing application of chemotherapy and traditional Chinese medicine: A meta-analysis. International Journal of Clinical Medical Research, 2025, 3, 63. doi:10.61466/ijcmr3040003
AMA Style
Mohamed B. M.. Treatment of non-small cell lung cancer with the nursing application of chemotherapy and traditional Chinese medicine: A meta-analysis. International Journal of Clinical Medical Research; 2025, 3(4):63. doi:10.61466/ijcmr3040003
Chicago/Turabian Style
Mohamed, Basma M. 2025. "Treatment of non-small cell lung cancer with the nursing application of chemotherapy and traditional Chinese medicine: A meta-analysis" International Journal of Clinical Medical Research 3, no.4:63. doi:10.61466/ijcmr3040003
APA style
Mohamed, B. M. (2025). Treatment of non-small cell lung cancer with the nursing application of chemotherapy and traditional Chinese medicine: A meta-analysis. International Journal of Clinical Medical Research, 3(4), 63. doi:10.61466/ijcmr3040003

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