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Open Access Journal Article

Relation between ABO and RhD and prevalence and severity of COVID-19 disease

by Ahmed M. Khalaf 1 ,  Marwa O. Elgendy 2,3,* ,  Alzhraa M. Fahmy 4 ,  Sara O. El Gendy 5 ,  Ahmed O. El-Gendy 6 ,  Mona A. Abdelrahman 7 ,  Ali H. El-Bahrawy 8 ,  Ahmed Mohammed M Elsisi 9,10  and  Shafiq Naguib Shafiq 1
1
Internal Medicine Department, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt
2
Department of Clinical Pharmacy, Beni-Suef University Hospitals, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt
3
Department of Clinical Pharmacy, Faculty of Pharmacy, Nahda University (NUB), Egypt
4
Tropical Medicine and Infectious Diseases Department, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt
5
Department of Clinical and Chemical Pathology, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt
6
Department of Microbiology and Immunology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt
7
Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt
8
Department of Clinical Pharmacy, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt
9
Biochemistry and Molecular Biology Department, Faculty of Pharmacy (Boys), Al-Azhar University, Nasr City, Cairo, Egypt
10
Biochemistry Department, Faculty of Pharmacy, Sinai University (SU), North Sinai, Al-Arish, Egypt
*
Author to whom correspondence should be addressed.
IJCMR  2024, 28; 2(3), 28; https://doi.org/10.61466/ijcmr2030003
Received: 12 February 2024 / Accepted: 5 May 2024 / Published Online: 7 May 2024
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Abstract

Backgrounds:

This study aims to determine the relation between ABO and RhD and the prevalence and severity of COVID-19 disease.

Methods:

Data of 495 SARS-CoV-2 infected patients admitted to hospitals were collected. The ABO and RhD were determined for each patient to detect any possible relation between the prevalence of SARS-CoV-2 infection and each blood group. The patients were followed up to determine oxygen saturation and surveillance outcome (died or improved) to detect any possible relation between the severity of COVID-19 disease and each blood group.

Results:

A+ blood group was found to have a percentage of 32.3%, O+ to have a percentage of 30.3%, B+ to have a percentage of 21.2%, and AB+ to have a percentage of 10.1%. 19% of all the patients died. 20% of the dead patients were with O+ blood group, 60.5% were with A+ blood group, 10% with B+ blood group and 5% were with O- blood group.

The mean ± SD oxygen saturation on hospital admission was 94.2 ± 6.2% for the patients with O+ blood group, 91.06 ± 7.5% for the patients with A+ blood group, 92.8 ± 6.9% for the patients with B+ blood group, 93.4 ± 3.5% for the patients with AB+ blood group, and 94.5 ± 5.9% for the patients with O- blood group.

Conclusion:

Blood group A+ was the most common in the COVID-19 patients followed by O+ then B+ then AB+. Patients with blood group A+ had the worst oxygen saturation at hospital admission and had a higher mortality rate.

Keywords: ;
Copyright: © 2024 by Khalaf, Elgendy, Fahmy, El Gendy, El-Gendy, Abdelrahman, El-Bahrawy, Elsisi and Shafiq. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (Creative Commons Attribution 4.0 International License). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ACS Style
Khalaf, A. M.; Elgendy, M. O.; Fahmy, A. M.; El Gendy, S. O.; El-Gendy, A. O.; Abdelrahman, M. A.; El-Bahrawy, A. H.; Elsisi, A. M. M.; Shafiq, S. N. Relation between ABO and RhD and prevalence and severity of COVID-19 disease. International Journal of Clinical Medical Research, 2024, 2, 28. https://doi.org/10.61466/ijcmr2030003
AMA Style
Khalaf A M, Elgendy M O, Fahmy A M, El Gendy S O, El-Gendy A O, Abdelrahman M A, El-Bahrawy A H, Elsisi A M M, Shafiq S N. Relation between ABO and RhD and prevalence and severity of COVID-19 disease. International Journal of Clinical Medical Research; 2024, 2(3):28. https://doi.org/10.61466/ijcmr2030003
Chicago/Turabian Style
Khalaf, Ahmed M.; Elgendy, Marwa O.; Fahmy, Alzhraa M.; El Gendy, Sara O.; El-Gendy, Ahmed O.; Abdelrahman, Mona A.; El-Bahrawy, Ali H.; Elsisi, Ahmed M. M.; Shafiq, Shafiq N. 2024. "Relation between ABO and RhD and prevalence and severity of COVID-19 disease" International Journal of Clinical Medical Research 2, no.3:28. https://doi.org/10.61466/ijcmr2030003

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