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cardiovascular anti-inflammatory infection polymers mucoadhesion mucosa Epithelial Diffusion Buccal binding interactions anticancer antibiotic mechanism of action pyrrolizine open appendectomy laparoscopy surgical site infection elderly split-thickness skin conventional therapy
Open Access Journal Article

The effect of laparoscopy versus open appendectomy on wound infection in elderly subject: A meta-analysis

by Mohammed A. Amin 1  and  Marina E. Boules 1,*
1
Department of Clinical Pharmacy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt
*
Author to whom correspondence should be addressed.
IJCMR  2024 2(5):39; https://doi.org/10.61466/ijcmr2050004
Received: 4 June 2024 / Accepted: 25 September 2024 / Published Online: 27 September 2024
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Abstract

Backgrounds

The purpose of the meta-analysis was to evaluate and compare the effect of laparoscopy versus open appendectomy on wound infection in elderly subjects.

Methods

The results of this meta-analysis were analyzed, and the odds ratio (OR) and mean difference (MD) with 95% confidence intervals (CIs) were calculated using dichotomous or contentious random or fixed effect models.

Results

For the current meta-analysis, 6 examinations spanning from 2004 to 2021 were included, encompassing 42675 people; of them, 15486 had a laparoscopy, and 27189 had an open appendectomy.

Laparoscopy had a significantly lower surgical site infection (OR, 0.27; 95% CI, 0.22-0.32, p<0.001) and intra-abdominal abscess (OR, 0.36; 95% CI, 0.31-0.42, p<0.001) compared to open appendectomy in elderly subjects.

Conclusions

The information that was looked at showed that in older people, laparoscopy had a much lower rate of surgical site infections and intra-abdominal abscesses than open appendectomy. However, given the small number of studies included, attention should be given to their values.

Keywords: elderly; surgical site infection; laparoscopy; open appendectomy;
Copyright: © 2024 by Amin and Boules. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (Creative Commons Attribution 4.0 International License). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ACS Style
Amin, M. A.; Boules, M. E. The effect of laparoscopy versus open appendectomy on wound infection in elderly subject: A meta-analysis. International Journal of Clinical Medical Research, 2024, 2, 39. doi:10.61466/ijcmr2050004
AMA Style
Amin M A, Boules M E. The effect of laparoscopy versus open appendectomy on wound infection in elderly subject: A meta-analysis. International Journal of Clinical Medical Research; 2024, 2(5):39. doi:10.61466/ijcmr2050004
Chicago/Turabian Style
Amin, Mohammed A.; Boules, Marina E. 2024. "The effect of laparoscopy versus open appendectomy on wound infection in elderly subject: A meta-analysis" International Journal of Clinical Medical Research 2, no.5:39. doi:10.61466/ijcmr2050004

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