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Open Access Original Study

The effect of laparoscopy versus open appendectomy on wound infection in elderly subject: A meta-analysis

by Mohammed A. Amin 1  and  Marina E. Boules 1,*
1
Department of Clinical Pharmacy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt
*
Author to whom correspondence should be addressed.
IJCMR  2024 2(5):39; https://doi.org/10.61466/ijcmr2050004
Received: 4 June 2024 / Accepted: 25 September 2024 / Published Online: 27 September 2024
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Abstract

Backgrounds

The purpose of the meta-analysis was to evaluate and compare the effect of laparoscopy versus open appendectomy on wound infection in elderly subjects.

Methods

The results of this meta-analysis were analyzed, and the odds ratio (OR) and mean difference (MD) with 95% confidence intervals (CIs) were calculated using dichotomous or contentious random or fixed effect models.

Results

For the current meta-analysis, 6 examinations spanning from 2004 to 2021 were included, encompassing 42675 people; of them, 15486 had a laparoscopy, and 27189 had an open appendectomy.

Laparoscopy had a significantly lower surgical site infection (OR, 0.27; 95% CI, 0.22-0.32, p<0.001) and intra-abdominal abscess (OR, 0.36; 95% CI, 0.31-0.42, p<0.001) compared to open appendectomy in elderly subjects.

Conclusions

The information that was looked at showed that in older people, laparoscopy had a much lower rate of surgical site infections and intra-abdominal abscesses than open appendectomy. However, given the small number of studies included, attention should be given to their values.

Keywords: elderly; surgical site infection; laparoscopy; open appendectomy;
Copyright: © 2024 by Amin and Boules. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (Creative Commons Attribution 4.0 International License). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ACS Style
Amin, M. A.; Boules, M. E. The effect of laparoscopy versus open appendectomy on wound infection in elderly subject: A meta-analysis. International Journal of Clinical Medical Research, 2024, 2, 39. https://doi.org/10.61466/ijcmr2050004
AMA Style
Amin M A, Boules M E. The effect of laparoscopy versus open appendectomy on wound infection in elderly subject: A meta-analysis. International Journal of Clinical Medical Research; 2024, 2(5):39. https://doi.org/10.61466/ijcmr2050004
Chicago/Turabian Style
Amin, Mohammed A.; Boules, Marina E. 2024. "The effect of laparoscopy versus open appendectomy on wound infection in elderly subject: A meta-analysis" International Journal of Clinical Medical Research 2, no.5:39. https://doi.org/10.61466/ijcmr2050004
APA style
Amin, M. A., & Boules, M. E. (2024). The effect of laparoscopy versus open appendectomy on wound infection in elderly subject: A meta-analysis. International Journal of Clinical Medical Research, 2(5), 39. https://doi.org/10.61466/ijcmr2050004

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References

  1. Addiss, D.G., Shaffer, N., Fowler, B.S., et al., The epidemiology of appendicitis and appendectomy in the United States. American journal of epidemiology, 1990. 132(5): p. 910-925.
  2. Chen, Y., Liu, Z., Li, X., et al., The aging trend of Chinese population and the prediction of aging population in 2015–2050. Chinese Journal of Social Medicine, 2018. 35(5): p. 480-483.
  3. Storm-Dickerson, T.L. and Horattas, M.C., What have we learned over the past 20 years about appendicitis in the elderly? The American journal of surgery, 2003. 185(3): p. 198-201.
  4. Bhullar, J.S., Chaudhary, S., Cozacov, Y., et al., Acute appendicitis in the elderly: diagnosis and management still a challenge. The American Surgeon, 2014. 80(11): p. 295-297.
  5. Podda, M., Gerardi, C., Cillara, N., et al., Antibiotic treatment and appendectomy for uncomplicated acute appendicitis in adults and children: a systematic review and meta-analysis. Annals of surgery, 2019. 270(6): p. 1028-1040.
  6. Semm, K., Endoscopic appendectomy. Endoscopy, 1983. 15(02): p. 59-64.
  7. Ukai, T., Shikata, S., Takeda, H., et al., Evidence of surgical outcomes fluctuates over time: results from a cumulative meta-analysis of laparoscopic versus open appendectomy for acute appendicitis. BMC gastroenterology, 2016. 16(1): p. 1-12.
  8. Mason, R.J., Moazzez, A., Sohn, H., et al., Meta-analysis of randomized trials comparing antibiotic therapy with appendectomy for acute uncomplicated (no abscess or phlegmon) appendicitis. Surgical infections, 2012. 13(2): p. 74-84.
  9. Lapsa, S., Ozolins, A., Strumfa, I., et al., Acute appendicitis in the elderly: a literature review on an increasingly frequent surgical problem. Geriatrics, 2021. 6(3): p. 93.
  10. Yuan, J., Chen, Q., Hong, W., et al., Comparison of clinical features and outcomes of appendectomy in elderly vs. non-elderly: A systematic review and meta-analysis. Frontiers in Surgery, 2022. 9: p. 818347.
  11. Wang, D., Dong, T., Shao, Y., et al., Laparoscopy versus open appendectomy for elderly patients, a meta-analysis and systematic review. BMC surgery, 2019. 19: p. 1-11.
  12. Liberati, A., Altman, D.G., Tetzlaff, J., et al., The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J. Clin. Epidemiol., 2009. 62(10): p. e1-e34.
  13. Higgins, J.P., Thompson, S.G., Deeks, J.J., et al., Measuring inconsistency in meta-analyses. Bmj, 2003. 327(7414): p. 557-560.
  14. Stroup, D.F., Berlin, J.A., Morton, S.C., et al., Meta-analysis of observational studies in epidemiology: a proposal for reporting. JAMA, 2000. 283(15): p. 2008-2012.
  15. Gupta, A., Das, A., Majumder, K., et al., Obesity is Independently Associated With Increased Risk of Hepatocellular Cancer–related Mortality. American journal of clinical oncology, 2018. 41(9): p. 874-881.
  16. Collaboration, C., RoB 2: A revised Cochrane risk-of-bias tool for randomized trials. Available at (Accessed December 6, 2019): bias/resources/rob-2-revised-cochrane-risk-bias-tool-randomized-trials, 2020.
  17. Sheikhbahaei, S., Trahan, T.J., Xiao, J., et al., FDG-PET/CT and MRI for evaluation of pathologic response to neoadjuvant chemotherapy in patients with breast cancer: a meta-analysis of diagnostic accuracy studies. The oncologist, 2016. 21(8): p. 931-939.
  18. Guller, U., Jain, N., Peterson, E.D., et al., Laparoscopic appendectomy in the elderly. Surgery, 2004. 135(5): p. 479-488.
  19. Wu, S.-C., Wang, Y.-C., Fu, C.-Y., et al., Laparoscopic appendectomy provides better outcomes than open appendectomy in elderly patients. The American Surgeon, 2011. 77(4): p. 466-470.
  20. Masoomi, H., Mills, S., Dolich, M.O., et al., Does laparoscopic appendectomy impart an advantage over open appendectomy in elderly patients? World journal of surgery, 2012. 36: p. 1534-1539.
  21. Yang, J., Yu, K., Li, W., et al., Laparoscopic appendectomy for complicated acute appendicitis in the elderly: a single-center experience. Surgical Laparoscopy, Endoscopy & Percutaneous Techniques, 2017. 27(5): p. 366-368.
  22. Wu, T.-C., Lu, Q., Huang, Z.-Y., et al., Efficacy of emergency laparoscopic appendectomy in treating complicated appendicitis for elderly patients. Saudi Medical Journal, 2017. 38(11): p. 1108.
  23. Dikicier, E., Mantoğlu, B., Özdemir, K., et al., Laparoscopy Versus Open Appendectomy for Elderly Patients: A Single-Center Experience. Sakarya Tıp Dergisi, 2021. 11(1): p. 1-8.
  24. Shchatsko, A., Brown, R., Reid, T., et al., The utility of the Alvarado score in the diagnosis of acute appendicitis in the elderly. The American Surgeon, 2017. 83(7): p. 793-798.
  25. Segev, L., Keidar, A., Schrier, I., et al., Acute appendicitis in the elderly in the twenty-first century. Journal of Gastrointestinal Surgery, 2015. 19: p. 730-735.
  26. Thoma, A. and Eaves III, F.F., A brief history of evidence-based medicine (EBM) and the contributions of Dr David Sackett. Aesthetic surgery journal, 2015. 35(8): p. NP261-NP263.
  27. Athanasiou, C., Lockwood, S., and Markides, G.A., Systematic review and meta-analysis of laparoscopic versus open appendicectomy in adults with complicated appendicitis: an update of the literature. World journal of surgery, 2017. 41: p. 3083-3099.
  28. Southgate, E., Vousden, N., Karthikesalingam, A., et al., Laparoscopic vs open appendectomy in older patients. Archives of Surgery, 2012. 147(6): p. 557-562.
  29. Baumann, L.M., Williams, K., Oyetunji, T.A., et al., Optimal timing of postoperative imaging for complicated appendicitis. Journal of Laparoendoscopic & Advanced Surgical Techniques, 2018. 28(10): p. 1248-1252.