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Comprehensive Analysis of Immune Responses in Recurrent Pregnancy Loss via Bioinformatics: A Big Picture

by Elham Abdollahi 1,*
1
Department of Biochemistry, University of Nebraska, Nebraska, USA
*
Author to whom correspondence should be addressed.
IJCMR  2025 3(2):54; https://doi.org/10.61466/ijcmr3020004
Received: 26 November 2024 / Accepted: 20 February 2025 / Published Online: 1 April 2025
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Abstract

Recurrent spontaneous abortion (RSA), a significant reproductive challenge, involves multiple pregnancy losses and impacts fertility. Although various factors contribute to RSA, immune system dysfunction is frequently implicated. Recent technological advancements in bioinformatics, particularly high-throughput sequencing and computational modeling, have enabled a more detailed examination of immune responses associated with RSA. This text explores how bioinformatics tools, including gene expression analysis, machine learning, and network analysis, facilitate the prediction of immune factors relevant to RSA. Additionally, it reviews current progress and potential future applications in personalized treatment strategies.

Keywords: Bioinformatics; Recurrent Spontaneous Abortion; Immunological Response; Transcriptomics; Systems Immunology; Biomarkers; Computational Modeling;
Copyright: © 2025 by Abdollahi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (Creative Commons Attribution 4.0 International License). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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APA Style
Abdollahi, E. (2025). Comprehensive Analysis of Immune Responses in Recurrent Pregnancy Loss via Bioinformatics: A Big Picture. International Journal of Clinical Medical Research, 3(2), 54. doi:10.61466/ijcmr3020004
ACS Style
Abdollahi, E. Comprehensive Analysis of Immune Responses in Recurrent Pregnancy Loss via Bioinformatics: A Big Picture. International Journal of Clinical Medical Research, 2025, 3, 54. doi:10.61466/ijcmr3020004
AMA Style
Abdollahi E. Comprehensive Analysis of Immune Responses in Recurrent Pregnancy Loss via Bioinformatics: A Big Picture. International Journal of Clinical Medical Research; 2025, 3(2):54. doi:10.61466/ijcmr3020004
Chicago/Turabian Style
Abdollahi, Elham 2025. "Comprehensive Analysis of Immune Responses in Recurrent Pregnancy Loss via Bioinformatics: A Big Picture" International Journal of Clinical Medical Research 3, no.2:54. doi:10.61466/ijcmr3020004

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ACS Style
Abdollahi, E. Comprehensive Analysis of Immune Responses in Recurrent Pregnancy Loss via Bioinformatics: A Big Picture. International Journal of Clinical Medical Research, 2025, 3, 54. doi:10.61466/ijcmr3020004
AMA Style
Abdollahi E. Comprehensive Analysis of Immune Responses in Recurrent Pregnancy Loss via Bioinformatics: A Big Picture. International Journal of Clinical Medical Research; 2025, 3(2):54. doi:10.61466/ijcmr3020004
Chicago/Turabian Style
Abdollahi, Elham 2025. "Comprehensive Analysis of Immune Responses in Recurrent Pregnancy Loss via Bioinformatics: A Big Picture" International Journal of Clinical Medical Research 3, no.2:54. doi:10.61466/ijcmr3020004
APA style
Abdollahi, E. (2025). Comprehensive Analysis of Immune Responses in Recurrent Pregnancy Loss via Bioinformatics: A Big Picture. International Journal of Clinical Medical Research, 3(2), 54. doi:10.61466/ijcmr3020004

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References

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