Issue 4 (August)

Backgrounds

A meta-analysis research was executed to appraise the effect of the continuous intervention for intraoperative pressure wound ulcers (IOPWUs) associated problems in breast cancer (BC) females.

Methods

Inclusive literature research till March 2023 was done and 436 interconnected researches were revised. The 8 picked researches, enclosed 1267 BC females were in the utilized researches' starting point, 636 of them were utilizing CI, and 631 were control. Odds ratio (OR) and 95% confidence intervals (CIs) were utilized to appraise the effect of CI for IOPWUs associated problems in BC females by the dichotomous, or contentious approaches and a fixed or random model.

Results

Continuous intervention had significantly lower IOPWUs (OR, 0.18; 95% CI, 0.13-0.24, p<0.001), higher Braden risk score (BRS) (OR, 2.11; 95% CI, 1.91-2.31, p<0.001), and higher quality of life (OR, 9.75; 95% CI, 6.90-12.60, p=0.02) compared to control in BC females.

Conclusions

Continuous intervention had significantly lower IOPWUs, higher BRS, and higher quality of life compared to control in BC females. However, caution must be taken when interacting with its values since there was a low number of nominated research found for some comparison in the meta-analysis.

Background:

A meta-analysis research was implemented to appraise gingival wound healing management by photobiomodulation as adjunctive management to periodontal treatments.

Inclusive literature research till April 2023 was done and 908 interconnected researches were revised. Methods

The 9 picked researches, enclosed 517 periodontal disease persons were in the utilized researchers' starting point, 258 of them were utilizing photobiomodulation, and 259 were control. Odds ratio (OR) and 95% confidence intervals (CIs) were utilized to appraise the consequence of photobiomodulation in treating gingival wound healing by the dichotomous, and contentious approach and a fixed or random model.

Results:

Photobiomodulation had a significantly higher Landry wound healing index (MD, 0.87; 95% CI, 0.40-1.34, p<0.001), and complete wound epithelialization (OR, 6.47; 95% CI, 2.05-20.44, p=0.001) compared to the control of gingival wound healing in periodontal disease persons. However, photobiomodulation and control had no significant difference in the remaining wound area (MD, -10.03; 95% CI, -22.83-2.77, p=0.12) of gingival wound healing in periodontal disease persons.

Conclusions:

Photobiomodulation had a significantly higher Landry wound healing index, and complete wound epithelialization, however, no significant difference was found in the remaining wound area compared to control of gingival wound healing in periodontal disease persons. However, caution needs to be taken when interacting with its values since there was a low sample size of most of the chosen research found for the comparisons in the meta-analysis and a low number of chosen investigations for some of the comparisons.

Background
The purpose of the meta-analysis was to evaluate and contrast Chinese herbal medicine's effectiveness as a supplement to conventional treatment for diabetic foot ulcers.
Methods
The results of this meta-analysis were analyzed using dichotomous or contentious random or fixed effect models, and the odds ratio (OR) and mean difference (MD) with 95% CIs were calculated. 1140 individuals with diabetic foot ulcers were included in the 17 exams that were enlisted for the current meta-analysis, which ran from 2006 to 2021.
Results
When compared to standard treatment, Chinese herbal medicine significantly increased the overall effective rate (OR, 2.77; 95% CI, 1.89-4.07, p<0.001), reduced the size of the wound after treatment (MD, -2.44; 95% CI, -3.46- -1.43, p<0.001), decreased the number of patients who did not improve (OR, 0.26; 95% CI, 0.15-0.45, p<0.001), and shortened the time it took for diabetic foot ulcers to heal (MD, -10.46; 95% CI, -14.91- -6.37, p<0.001). The number of patients who experienced a 30% or greater decrease in the ulcer area of their diabetic foot ulcer did not, however, differ significantly between Chinese herbal medicine and standard treatment (OR, 2.69; 95% CI, 0.70-10.30, p=0.15).
Conclusions
According to the data analyzed, Chinese herbal medicine had a significantly higher overall effective rate, a smaller post-treatment wound, fewer patients who did not improve, and a shorter healing period for diabetic wound ulcers. However, there were no appreciable differences in the number of patients who experienced ulcer area reductions of 30% or more when compared to standard treatment for diabetic foot ulcers. However, given the majority of the chosen tests had small sample sizes and certain comparisons had few chosen studies, care should be taken when connecting to its values.

Backgrounds

The meta-analysis aims to estimate the effect of antibiotic prophylaxis (AP) on surgical site wound infection (SSWI) in third molar surgery (TMS).

Methods

Examinations comparing AP to placebo for TMS were utilized in the meta-analysis from various languages that met the inclusion criteria. Using dichotomous random or fixed effect models, the results of these investigations were examined, and the Odd Ratio (OR) with 95% confidence intervals was computed (CIs).

18 examinations from 2001 to 2023 were recruited for the current analysis including 4063 personals with TMS who were in the utilized examinations' starting point.

Results

AP had significantly lower SSWI (OR, 0.46; 95% CI, 0.33-0.65, p<0.001) with no heterogeneity (I² = 1%) compared to placebo in personals with TMS.

Conclusions

The examined data revealed that AP had significantly lower SSWI compared to placebo in personals with TMS. Nevertheless, caution should be exercised while interacting with its values since examinations were performed by different surgeons with different skills on different types of personals and the low sample size of numerous of the examinations selected for the meta-analysis.

Background

We performed a meta-analysis to evaluate the influence of a phosphate-specific intake on serum phosphate levels in hemodialysis subjects.

Methods

A systematic literature search up to November 2021 was done and 14 studies included 1284 hemodialysis subjects at the start of the study; 671 of them were provided with phosphate-specific intake, and 613 were control. We calculated the mean difference (MD) with 95% confidence intervals (CIs) to evaluate the influence of phosphate-specific intake on serum phosphate levels in hemodialysis subjects by the contentious method with a random or fixed-influence model.

Results

Phosphate-specific intake had significantly better serum phosphate levels change (MD, -0.66; 95% CI, -0.95- -0.36, p<0.001) with moderate heterogeneity (I² = 71%) compared to control in hemodialysis subjects

Conclusions

Phosphate-specific intake had significantly lower serum phosphate levels change compared to control in hemodialysis subjects. Further studies are required.