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A meta-analysis on the use of photobiomodulation to regulate gingival wound healing in addition to periodontal therapies

by Yaieo Koang 1,*
Department of Stomatology, Xinxeiang Central Hospital, The Fourth Clinical College of Xinxeiang Medical University, Henan, 453000, China
Author to whom correspondence should be addressed.
IJCMR  2024, 32; 2(4), 32;
Received: 21 May 2024 / Accepted: 22 July 2024 / Published Online: 10 July 2024



A meta-analysis research was implemented to appraise gingival wound healing management by photobiomodulation as adjunctive management to periodontal treatments.

Inclusive literature research till April 2023 was done and 908 interconnected researches were revised. Methods

The 9 picked researches, enclosed 517 periodontal disease persons were in the utilized researchers' starting point, 258 of them were utilizing photobiomodulation, and 259 were control. Odds ratio (OR) and 95% confidence intervals (CIs) were utilized to appraise the consequence of photobiomodulation in treating gingival wound healing by the dichotomous, and contentious approach and a fixed or random model.


Photobiomodulation had a significantly higher Landry wound healing index (MD, 0.87; 95% CI, 0.40-1.34, p<0.001), and complete wound epithelialization (OR, 6.47; 95% CI, 2.05-20.44, p=0.001) compared to the control of gingival wound healing in periodontal disease persons. However, photobiomodulation and control had no significant difference in the remaining wound area (MD, -10.03; 95% CI, -22.83-2.77, p=0.12) of gingival wound healing in periodontal disease persons.


Photobiomodulation had a significantly higher Landry wound healing index, and complete wound epithelialization, however, no significant difference was found in the remaining wound area compared to control of gingival wound healing in periodontal disease persons. However, caution needs to be taken when interacting with its values since there was a low sample size of most of the chosen research found for the comparisons in the meta-analysis and a low number of chosen investigations for some of the comparisons.

Copyright: © 2024 by Koang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (Creative Commons Attribution 4.0 International License). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ACS Style
Koang, Y. A meta-analysis on the use of photobiomodulation to regulate gingival wound healing in addition to periodontal therapies. International Journal of Clinical Medical Research, 2024, 2, 32.
AMA Style
Koang Y. A meta-analysis on the use of photobiomodulation to regulate gingival wound healing in addition to periodontal therapies. International Journal of Clinical Medical Research; 2024, 2(4):32.
Chicago/Turabian Style
Koang, Yaieo 2024. "A meta-analysis on the use of photobiomodulation to regulate gingival wound healing in addition to periodontal therapies" International Journal of Clinical Medical Research 2, no.4:32.

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